Sr Principal Scientist - Standardized Organoid Modeling Center

Company: Frederick National Laboratory for Cancer Research
Location: Frederick
Posted on: April 2, 2026

Job Description:

Sr Principal Scientist - Standardized Organoid Modeling Center Job ID: req4510 Employee Type: exempt full-time Division: Laboratory Animal Science Program Facility: Frederick: Ft Detrick Location: PO Box B, Frederick, MD 21702 USA The Frederick National Laboratory is operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way. PROGRAM DESCRIPTION The Laboratory & Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for laboratory and animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of husbandry, veterinary, state-of-the-art technology, and pre-clinical scientific services. KEY ROLES/RESPONSIBILITIES This Senior Principal Scientist organoid position (Major Equipment and Assay Development) is expected to investigate ways of standardizing the growth of normal (non-cancerous) human organoids, to utilize organoids to model and study human disease, and to perform and publish independent research. Initiates, directs, and executes all pre-clinical scientific research and/or development strategies. Exercises independent judgment in developing methods, techniques, and evaluation criteria for obtaining results. Expert knowledge of scientific principles and concepts. Reputation as emerging leader in field with sustained performance and accomplishment. Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products, and problems. Acts as a resource for colleagues with less experience; directs the work of other staff members. Exercises latitude in determining objectives and approaches to critical assignments. Maintains broad knowledge of state-of-the-art principles and theories. Makes major contributions to scientific literature and conferences. Implements solutions that require a long-term view and consideration of multiple perspectives and future impact. Solves unique and complex problems that have a broad impact on the business. May act as a spokesperson on corporate research and development and advise top management. May participate in the development of patent applications. Interfaces with various departments and serves as an internal consultant. Accountable for meeting own targets which will impact the discipline BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below: Possession of a PhD degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA). Foreign degrees must be evaluated for U.S. equivalency. In addition to the education requirement, a minimum of ten (10) years of progressively responsible experience. Strong evidence of previous scientific mentoring and laboratory leadership. Must possess basic Microsoft Office skills. Ability to obtain and maintain a security clearance. PREFERRED QUALIFICATIONS Candidates with these desired skills will be given preferential consideration: Has directed the pre-clinical research efforts of other scientists in organoid or stem cell research. JOB HAZARDS This position is subject to working with or has the potential for exposure to infectious material, requiring medical clearance and immunizations. Commitment to Non-Discrimination All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, color, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws. Pay and Benefits Pay and benefits are fundamental to any career decision. That's why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available here 166,100 - 290,700 USD The posted pay range for this job is a general guideline and not a guarantee of compensation or salary. Additional factors considered in extending an offer include, but are not limited to, responsibilities of the job, education, experience, knowledge, skills, and abilities as well as internal equity, and alignment with market data. The salary range posted is a full-time equivalent salary and will vary depending on scheduled hours for part time positions

Keywords: Frederick National Laboratory for Cancer Research, Bel Air North , Sr Principal Scientist - Standardized Organoid Modeling Center, Science, Research & Development , Frederick, Maryland